Breast cancer is the second leading cause of cancer death in women, exceeded only by lung cancer. A study recently published in the journal Breast Cancer examined the effects of a blended natural supplement on breast health in 96 pre- and post-menopausal women not taking hormonal contraceptives, supplements, or HRT. The randomized controlled trial, published by Canadian researcher Maggie Laidlaw, used a novel biomarker called the carcinogenic ratio. A follow-up study will be funded by the Canadian government. The breast health supplement used was derived from stinging nettle and contained HMR lignan, indole-3-carbinol, calcium glucarate, and milk thistle.