Aging

Anti-Aging Possibility

Tyrosine is one of the amino acids which is a building block of protein. The body makes it from another amino acid called phenylalamine. It can be used to treat depression, ADD, ADHD, stress, PMS, chronic fatigue syndrome, etc. It improves mental alertness and depression. A topical preparation containing tyrosine and ascorbic acid is being tried to treat aging, yellowing, and wrinkled skin on the face.

Melatonin and Macular Degeneration

The potential of melatonin to treat or prevent age-related macular degeneration through stimulation of telomerase activity: Response to injury in the retinal pigment epithelium is compromised during aging. Prevention of telomere shortening by antioxidants may be a useful approach for reducing the cumulative effects of oxidative stress in RPE cells. Melatonin cream applied to the face has been suggested as the method of choice, as well as tracking melatonin blood levels and eating melatonin rich foods.

From Med Hypothesis. 2011 E Pub 2010 Sept. 29.

The Mother of Hormones

What is DHEA and what does it do? Dehydroepiandrosterone is a hormone produced by the adrenal gland and the skin. It is a precursor for many other hormones (hence the title ‘Mother of All Hormones,’ which shifts the body-s metabolism from a catabolic one of breakdown and fat storage – to an anabolic one.

It has been shown to slow down the aging process in lab animals. DHEA is also known to improve the symptoms of lupus, and there is currently a pending FDA study for approval of this very function. The best source I have found is Twist 25.

DHEA Sulfate blood levels should be monitored periodically. Levels that are too high could cause acne in men or peach fuzz hirsutism in women.

Pills to Keep Us Young

Can a pill keep your DNA young? An article in DISCOVER magazine, May 2010, is thought provoking. Telomeres, repeating DNA sequences at the ends of chromosomes, which shorten with each cell division, eventually shorten to a point where the cell stops dividing and dies. A molecule from the herb astragalus is being marketed as TA-65, in pill form, and is being tested for athletic, visual, and cognitive performance. The marketing company hopes to have an approved drug within 15 years.

Anti-Aging

Mice engineered to lack the enzyme called telomerase become prematurely decrepit. They bounce back to health when the enzyme is replaced. This comes from the Dana Farber Institute and Harvard and has implications for anti-aging. Short telomers lead to early death, many researchers argue. Others disagree.

Accidents?

Chance and the prepared mind are key elements to drug discovery. One of the best examples of this phenomenon was the emergence of the blockbuster drug Viagra when Pfizer researchers, who were searching for entirely unrelated drugs, stumbled upon it several years ago. As Louis Pasteur, a founder of microbiology, remarked centuries earlier, “chance favors the prepared mind.”

A drug has now emerged in the same manner as Viagra. It is named INTUNIV. This medication clears harmful senescent cells from the body leading to delay in age-related conditions. Source: “Aging Gracefully” by Amanda Chan, The Huffington Post, November 3, 2011.

Questions Answered About DHEA

How to Use DHEA?

Why DHEA supplement cream works better than pills?

Is DHEA Safe?

Twist 25 DHEA cream is the highest quality most effective anti-aging and wellness product available.

Health2Go, Inc. hired a PhD chemist with 18 years experience formulating and compounding topical specially made creams to develop and test Twist 25 DHEA cream. The requirements were set very high. There were 17 versions of the cream considered to develop the best possible cream mix.

Twist 25 cream is a highly specialized custom engineered emulsion cream in a coconut oil base  that delivers pharmaceutical grade bio-identical DHEA by simply rubbing the cream onto thin hairless skin so that DHEA is available at the ideal place in the dermis for best absorption and metabolism.  The small particle size makes Twist 25 cream unique allowing for optimal delivery of DHEA and a long shelf life. Safety studies were done for 90 days. Study participants had no irritations or adverse reactions to the cream. So you can have confidence in Twist 25 DHEA supplement cream knowing Health2Go, Inc. only sells the best possible DHEA cream. It’s not the cheapest. It’s the best. It works.

Recent medical research studies show DHEA must be delivered to the body as a specially made cream rather than as a pill supplement. There are 3 key reasons for this.

Reason 1) When taken as a pill, orally ingested DHEA is destroyed by the “first-pass effect” of the liver. Basically, this means that because the molecule is too large it appears to be a foreign substance, the liver filters most of the effective DHEA out before it can do any good: and, what does end up getting into the bloodstream is DHEA-S (DHEA sulphate).

Reason 2) DHEA-S is not the same as DHEA. DHEA-S is a different pro-hormone and has different benefits than DHEA. New medical research shows DHEA-S is not converted by the body into DHEA. However, DHEA is converted into DHEA-S, but not the other way around.

Twist 25 does supplement DHEA instead rather than DHEA-S.

(Fabian Hammer, Sandra Subtil, Philipp Lux, Christiane Maser-Gluth, Paul M. Stewart, Bruno Allolio and Wiebke Arlt. No Evidence for Hepatic Conversion of Dehydroepiandrosterone (DHEA) Sulphate to DHEA: In Vivo and in Vitro Studies. Journal of Clinical Endochrinology and Metabolism Vol. 90, No. 6 3600-3605)

So the majority of research studies of “DHEA” administered via oral DHEA supplements and consequently showed little benefit to “DHEA”(Sulphate) were not testing DHEA with an effective method of administration.

DHEA must be delivered to the body properly as a specially made DHEA cream – Twist 25.

Reason 3) Medical research shows the human body metabolizes DHEA into other hormones in the skin (the dermis). The skin is where we make and use much of the DHEA we make. So Twist 25 cream actually provides what the body produces naturally (bio-identical DHEA) where we use it (in the skin).

(Labrie F, Belanger A, Belanger P, Berube R, Martel C, Cusan L, Gomez J, Candas B, et al. Metabolism of DHEA in Postmenopausal women following percutaneous administration. Journal of Steroid Biochemistry & Molecular Biology, 103 (Feb 2007) pp 178-188) www.ncbi.nlm.nih.gov/pubmed/17084625

(Labrie F, Belanger A, Cusan L, Candas L intraPhysiological Changes in Dehydroepiandrosterone Are Not Reflected by Serum Levels of Active Androgens and Estrogens But Their Metabolites: Intracrinology. Journal of Clinical Endocrinology and Metabolism. Vol. 82 No. 8, pgs 2403-2409)http://press.endocrine.org/dol/pdf/10.1210/jcem.82.8.4161

(Labrie F, Labrie C. DHEA and intracrinology at menopause, a positive choice for evolution of the human species.) www.ncbi.nlm.nih.gov/pubmed/23126249

DHEA must be delivered to the body properly as a specially made DHEA cream – Twist 25.

To know DHEA supplementation is safe think it through logically. DHEA is a naturally occurring pro-hormone. It is the most abundant pro-hormone in the body. DHEA is a base building block for hormones we produce. 50 hormones use DHEA as a precursor. The body makes DHEA and pregnenalone from cholesterol.

Why would something the body produces be harmful. No medical research studies of DHEA have shown any dangerous or harmful effects.

The goal should be to maintain levels of DHEA as when we are at our healthiest, “in our prime”. Normal levels of DHEA at age 25 are about 350 micrograms for women and 550 micrograms for men. Each pump press of Twist 25 DHEA cream provides about 20 MG DHEA. So women age 35 and up would benefit from using at least 1-2 pump presses per day; and men 2-3 pump presses per day unless otherwise directed by your physician. Testing levels regularly with a blood spot test is recommended to ensure optimum levels are maintained.

Go to www.twist25.com to learn more or http://store.twist25.com to order on line.

I am not compensated in any way for sales of Twist 25 cream. Please see my websites at www.abouthormones.org and dheafacts.com for my advice about current medical science.

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